MATRx Oral Appliance Titration Technology Moving Closer to In-Home Applications

posted May 22, 2015, 11:39 AM by Admin SRSAN   [ updated May 22, 2015, 11:41 AM ]

The introduction of Zephyr Sleep Technologies' MATRx titration system in 2012 revolutionized the field of dental sleep medicine. For the first time, a single-night test in the sleep lab allowed the treating provider to determine with a high degree of accuracy whether the patient would respond to a mandibular repositioning device, as well as the target protrusive position required to achieve successful resolution of the obstructive sleep apnea. This approach allowed treating dentists and physicians to select those cases with a high probability of success, advance much more rapidly to the therapeutic position and avoid over-titration - reducing side effects and delivering effective treatment from day one - comparable to CPAP therapy.

The MATRx system uses a custom-fitted mandibular repositioning appliance that is remote-controlled by a sleep technician during a one-night polysomnogram session, according to a precise protocol which produces small incremental adjustments in mandibular position without disrupting the patient's sleep. In keeping with industry trends, this groundbreaking technology is now being adapted for in-home titration tests: the Zephyr team led by Dr. John Remmers has just completed a new clinical trial (150 patients) "demonstrating the feasibility of carrying out a computer-controlled mandibular titration (CCMP) test safely in an unattended setting, with an accuracy comparable to MATRx". With the clinical trial complete, the company is now moving into the product development stage, according to Paul Cataford, CEO and co-founder of Zephyr.

Source: http://zephyrsleep.com/award-winning-research/